Best Nighttime Sinus Medicine

How To Find The Best Nighttime Sinus Medicine?

After hours of researching and using all the models on the market, we find the Best Nighttime Sinus Medicine of 2022. Check out our ranking below!

Top 10 Best Nighttime Sinus Medicine in 2022

$6.59
$7.49
in stock
6 new from $6.55
as of May 2, 2022 7:58 pm
Amazon.com
$22.99
in stock
6 new from $19.80
as of May 2, 2022 7:58 pm
Amazon.com
$9.24
in stock
3 new from $9.24
as of May 2, 2022 7:58 pm
Amazon.com
$8.33
$12.49
in stock
5 new from $8.09
as of May 2, 2022 7:58 pm
Amazon.com
$6.62
in stock
3 new from $6.62
as of May 2, 2022 7:58 pm
Amazon.com
$4.87
$8.00
in stock
11 new from $4.82
as of May 2, 2022 7:58 pm
Amazon.com
$16.88
in stock
2 new from $16.88
as of May 2, 2022 7:58 pm
Amazon.com
$18.99
in stock
7 new from $17.30
as of May 2, 2022 7:58 pm
Amazon.com
$21.99
in stock
8 new from $17.76
as of May 2, 2022 7:58 pm
Amazon.com
Last updated on May 2, 2022 7:58 pm

List the Best Nighttime Sinus Medicine in 2022

Sudafed PE Day and Night Sinus Pressure & Congestion Tablets, 20 Count

$7.49
$6.59
 in stock
6 new from $6.55
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • 20-count of Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Medicine Tablets to temporarily relieve sinus pressure and sinus congestion for both day and night
  • Each multi-pack contains 20 tablets of nasal decongestant, with 12 Daytime and 8 Nighttime tablets for powerful symptom relief throughout the day and while you sleep
  • Each daytime and nighttime dose contains 10 milligrams of the nasal decongestant phenylephrine HCl per tablet and each nighttime dose also contains 25 milligrams per tablet of the antihistamine diphenhydramine HCl
  • Both formulas help relieve sinus pressure and sinus congestion, and nasal congestion due to the common cold, hay fever, or upper respiratory allergies. Nighttime tablets also relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose
  • From the #1 pharmacist recommended brand among oral OTC decongestants, this maximum-strength formula can be used by adults and children 12 years and older for powerful symptom relief

Mucinex Sinus-Max Maximum Strength Day and Night, Sinus Symptom Relief, 40 Count

$22.99  in stock
6 new from $19.80
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • Day caplets help relieve sinus pressure, congestion and headache, plus thin and loosen mucus
  • Night helps to alleviate nasal congestion, sinus pressure, pain, running nose, sneezing and control cough so you're able to get to sleep
  • Maximum strength formula
  • Includes 40 caplets (24 Day caplets and 16 Night caplets)

ALKA-SELTZER PLUS Maximum Strength PowerMax Allergy and Cough Medicine, Liquid Gels for Adults with Pain Reliever, Fever Reducer, Cough Suppressant, Antihistamine, Nasal Decongestant, 24 Count

$9.24  in stock
3 new from $9.24
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • New 25% smaller pill: Alka-Seltzer Plus Maximum Strength severe sinus, allergy & Cough Powermax gels have a concentrated formula to provide powerful fast relief
  • Get the fast, effective allergy symptom relief you need, when you need it
  • Powerful, multi-symptom relief for your worst allergies, including sinus congestion, headache, sneezing, cough, sinus pressure, runny nose, and itchy, watery eyes
  • Fast relief so you can get back to your busy life
  • Use as directed.

MUCINEX Nightshift Sinus 6 fl. oz. Relieves Fever, Sore Throat, Runny Nose, Sneezing, Nasal Congestion, and Controls Cough

$12.49
$8.33
 in stock
5 new from $8.09
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • SINUS RELIEF: Mucinex Nightshift Sinus helps reduce fever, relieve pain, headache, cough, runny nose, sneezing and sore throat, nasal congestion
  • #1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust for themselves and their families
  • PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain
  • COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough
  • NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

Rite Aid Multi-Symptom Nighttime Cold & Flu Relief, Softgels - 48 Count | Pain, Aches, Fever and Cough Relief | Sinus Medicine for Adults | Real Time Pain Relief | Mucus Relief | Sinus Headache Relief

$9.99  in stock
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • MULTI-SYMPTOM RELIEF: You’ll feel nighttime relief from aches, fever, coughing, sneezing, and runny nose associated with cold and flu. Compare Rite Aid Pharmacy’s Nighttime Cold & Flu Relief softgels to the active ingredients in top national brands fighting night time cold and flu symptoms.
  • NIGHTTIME FORMULA: Rite Aid Nighttime Cold & Flu Relief softgels offer temporary sinus headache relief, relief from fever, aches, coughs, and sneezing. Plus, you’ll get restful sleep at night thanks to our nighttime formulated sinus medicine for adults.
  • FEVER & PAIN RELIEVER: 325mg of Acetaminophen in each softgel temporarily relieves common cold symptoms like minor aches and pains, headache, sore throat, and fever— while cough suppressant and antihistamine calm your sinuses and throat so you can sleep.
  • ONLY 3 ACTIVE INGREDIENTS: Easy on your body, effective on your cold. Rite Aid’s Cold & Flu only has 3 active ingredients— pain reliever/fever reducer, Acetaminophen; cough suppressant, Dextromethorphan HBr; and antihistamine, Doxylamine Succinate.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.

Alka-Seltzer Plus Severe Night Cold PowerFast Fizz Effervescent Tablets 20ct

$6.62  in stock
3 new from $6.62
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • Unbeatably Fast* Cold Relief . Among oral products. Use as directed
  • Our severe Cold Night formula provides fizzy fast nighttime relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, cough, headache, fever, sore throat and body aches & pains.
  • Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
  • Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
  • Comes in Effervescent form, with a refreshing Lemon flavor. Use as directed.

Alka-seltzer Plus Cold & Flu, Power Max Cold and Flu Medicine, Night, For Adults with Pain Reliever, Fever Reducer, Cough Suppresant, Nasal Decongestant, Antihistamine, 36 Count

$8.00
$4.87
 in stock
11 new from $4.82
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • 25% smaller pill: Alka-Seltzer Plus Maximum Strength cold & Flu Powermax gels have a concentrated formula to provide powerful fast relief
  • Maximum strength day time and night time relief from your worst cold & Flu symptoms
  • Day time multi-symptom relief of nasal congestion, cough, headache, body ache, sore throat, Sinus pressure and fever. Night time multi-symptom relief of runny nose, nasal congestion, cough, headache, body ache, sore throat and fever.
  • Fast relief so you can get back to your busy life
  • Use as directed.

Vicks NyQuil LiquiCaps, Nighttime Relief of Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, 48 LiquiCaps

$16.88  in stock
2 new from $16.88
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • POWERFUL NIGHTTIME RELEIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold and flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing
  • RELIEVES YOUR COLD SYMPTOMS SO YOU CAN SLEEP BETTER. NyQuil helps to relieve your cold & flu symptoms, so you can get the rest you need
  • #1 PHARMACIST RECOMMENDED over-the-counter cold & cough medicine from Vicks, the world’s #1 selling cough & cold brand
  • MULTI-SYMPTOM RELIEF. NyQuil Cold & Flu contains a nasal decongestant for your toughest nasal congestion and sinus pressure
  • CONTAINS ACETAMINOPHEN: A pain reliever/fever reducer than can help soothe your sore throat

Mucinex Sinus-Max Max Strength Day & Night Liquid Gels (24ct) Relieves Sinus Pressure and Congestion, Headaches, Pain, Runny Nose, Sneezing, Thins and Loosens Mucus, Controls Cough

$18.99  in stock
7 new from $17.30
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • Day Time: relieves sinus pressure, congestion, headache, and thins and loosens mucus
  • Night Time: relieves nasal congestion, sinus pressure, pain, runny nose, sneezing, and controls cough
  • Maximum strength formula
  • Fast dissolving liquid gels
  • 24 count (16ct day time liquid gels, 8ct night time liquid gels)

Maximum Strength Mucinex Fast-Max Day Cold & Flu & Nightshift Night Severe Cold & Flu All In One, Fast Release, Powerful Multi-Symptom Relief, 40 caplets (24 Day time + 16 Night time)

$21.99  in stock
8 new from $17.76
Free shipping
Amazon.com
as of May 2, 2022 7:58 pm

Features

  • MAXIMUM STRENGTH MUCINEX FAST-MAX DAY COLD and FLU and NIGHTSHIFT NIGHT SEVERE COLD and FLU: Fast Release, Powerful Multi-Symptom Relief medicine. 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine
  • DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal and sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat
  • NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Nightshift Severe Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose, sore and itchy throat and allergy symptoms
  • No.1 TRUSTED COLD and COUGH BRAND: No.1 Cold and Cough brand doctors trust for themselves and their families and No.1 Pharmacist Recommended Expectorant
  • DAY TIME ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen - Pain reliever; Dextromethorphan HBr - Cough Suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal Decongestant

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